The Canada Excellence Research Chair in Data Science for Real-Time Decision-Making aims at developing new tools and methodologies that will allow enormous volumes of data from multiple sources to be processed and analyzed in real time — in order to obtain usable knowledge and to automate decision-making. By combining processes for analyzing highly targeted data and real-time decision-making, their mathematical model-based tools will help organizations improve performance, by creating highly customized outputs and taking into account the environments, needs and individual behaviors of their clients or users. The applications that result will foster new business models that are based on accurate depictions of user behaviors and expectations, combined with competitors’ responses. The many sectors that could benefit include transportation management, energy, health care and manufacturing, as well as supply chain management and logistics.